RAD 150 Review: What RAD-150 (TLB-150) Is and What Is Actually Known

RAD-150 (TLB-150) is sold as a newer, stronger form of RAD-140, but it has no published research at all: no human trial, no animal study and no published lab analysis of what RAD-150 products contain (ClinicalTrials.gov). PubChem files the name under “TLB 150 benzoate”, a benzoate ester of RAD-140 that appears in a Radius Health patent, where it bound the androgen receptor about 65 times more weakly than RAD-140 (PubChem CID 68547459; US patent 8,629,167). Claims that it is stronger, longer-acting or safer than RAD-140 are unproven. It is not approved anywhere, and anti-doping agencies treat it as a banned SARM (UK Anti-Doping).

Below: what RAD-150 is, the name confusion, everything that is (and is not) known, how it compares with RAD-140, what its side effects might be, its legal status, and what to check before buying it.

What is RAD-150 (TLB-150)?

Sellers use RAD-150 and TLB-150 for the same product. PubChem lists RAD150 as a synonym of “TLB 150 benzoate” (CID 68547459), with the formula C27H20ClN5O3: that is RAD-140 (C20H16ClN5O2) with a benzoyl group attached to its hydroxyl group, in other words RAD-140 benzoate (PubChem CID 68547459; PubChem CID 44200882). The same molecule is Example 87 of US patent 8,629,167 from Radius Health, the company that developed RAD-140, where it was made from RAD-140 and benzoyl chloride (US patent 8,629,167).

There is a catch: a PubChem search for “RAD-150” or “Rad 150” returns a different record (CID 32771), an unrelated chemical that happens to share the name (PubChem CID 32771). And because no published lab analysis of products sold as RAD-150 exists, which molecule a given bottle contains has not been established.

Is RAD-150 a steroid or a peptide?

Neither. As listed by PubChem it is a nonsteroidal SARM ester, built on RAD-140’s nonsteroidal structure (PubChem CID 68547459). UK Anti-Doping lists RAD-150 (TLB-150) among SARMs (UK Anti-Doping).

RAD-150 research: what exists

For context, RAD-140 itself has only one small human trial, in women with breast cancer (LoRusso 2022). See both in the SARMs database.

RAD-150 vs RAD-140

“Stronger” is not supported: in the only test on record, RAD-150 bound the androgen receptor much more weakly than RAD-140. “Longer-acting” is not supported either: no one has measured its half-life. Whether the body converts RAD-150 back into RAD-140 has never been tested. Our full comparison: RAD-140 vs RAD-150.

RAD-150 benefits: claims vs evidence

Muscle growth, strength, endurance and fat loss are the usual claims. None has been tested in cells, animals or people (ClinicalTrials.gov). RAD-140’s own muscle evidence comes from rats and young monkeys, not people (Miller 2011), so even the parent drug’s benefits in humans are unmeasured.

RAD-150 results and before-and-after reports

There are no measured results. Photos and reviews cannot show what RAD-150 does, especially since no published lab test confirms what RAD-150 products contain. For what RAD-140 users report, with the evidence alongside, see RAD-140 before and after.

RAD-150 side effects

Unknown, because it has not been studied (ClinicalTrials.gov). What can be said:

• Possible RAD-140 risks (theoretical). If the body turns RAD-150 back into RAD-140, which nobody has tested, RAD-140’s documented harms would be relevant: liver-enzyme rises in about half of its trial patients (LoRusso 2022) and case reports of liver injury (Leung 2022) and heart inflammation (Padappayil 2022).
• Harms linked to SARM products. The FDA says life-threatening reactions, including liver injuries needing hospital care, have occurred in people taking SARM products, and lists possible risks including heart attack or stroke, liver failure, infertility and testicular shrinkage (FDA).
• Mislabeling. In a test of 44 products sold online as SARMs, only 52% contained a SARM and 25% contained substances not on the label (Van Wagoner 2017).

Does RAD-150 cause hair loss or gyno?

Not known. No study has looked at hair loss, gyno or any other effect of RAD-150. What is known across SARMs: SARMs and hair loss, do SARMs cause gyno? and SARMs side effects.

Does RAD-150 suppress testosterone? Do you need PCT?

No study has measured hormones with RAD-150 (ClinicalTrials.gov). It does bind the androgen receptor in the patent assay (US patent 8,629,167), and RAD-140 lowered testosterone by about two-thirds in young male monkeys (Miller 2011), so suppression would not be surprising, but it has not been measured. What is known about recovery and the PCT drugs that have been studied: PCT after SARMs, RAD-140 PCT and the PCT and bloodwork planner. Markers worth knowing about are in our SARMs bloodwork guide.

RAD-150 dosage and half-life

No dosing study of any kind exists for RAD-150, in people or animals, and no half-life has been measured (ClinicalTrials.gov). Claims of a longer half-life than RAD-140 are not backed by any published data. Products are sold by label strength; SwissChems, for example, sells RAD-150 (TLB-150) as 10 mg capsules. For RAD-140’s trial doses, see RAD-140 dosage.

Is RAD-150 legal?

• United States: not FDA-approved. RAD-150 is not named in the FDA notices we found, but the FDA says products sold as SARMs are unapproved drugs, not dietary supplements (FDA).
• United Kingdom: UK Anti-Doping lists RAD-150 (TLB-150) among commonly available SARMs. It says no SARM is approved for human use and that SARMs are illegal to sell or advertise as food or in supplements (UK Anti-Doping).
• Australia: not named, but SARMs as a class are prescription-only (Schedule 4) and possession without authority is illegal (Poisons Standard 2026).
• Germany: the Anti-Doping Act’s annex names RAD-140 and states that the list includes esters and other derivatives of the listed substances (AntiDopG annex); PubChem lists RAD-150 as a benzoate ester of RAD-140 (PubChem CID 68547459).
• France and elsewhere: it is not an approved medicine anywhere, so there is no prescription or pharmacy version.

More: are SARMs legal? and SARMs in Europe.

RAD-150 in sport and drug tests

RAD-150 is not named on WADA’s 2026 List, but S1.2 bans SARMs as a class (“including, but not limited to” the named examples) (WADA 2026), and UK Anti-Doping lists RAD-150 (TLB-150) as a prohibited SARM (UK Anti-Doping). We found no published anti-doping study on RAD-150 itself. See SARMs and WADA and SARMs drug test.

Buying RAD-150: what to check

Because no published analysis shows what products sold as RAD-150 contain, the certificate of analysis matters even more than usual: it should name the compound, the lot and the lab, and confirm identity by mass spectrometry. Learn how to read a lab test. Our current pick for SARMs is SwissChems, which publishes lot-specific lab reports; see our SwissChems review and where to buy SARMs.

Bottom line

RAD-150 is a name with almost nothing behind it. The molecule PubChem files under that name is an ester of RAD-140 that, in the only test on record, bound the androgen receptor about 65 times more weakly than RAD-140. There are no studies of its effects, safety, half-life or dose, no published analysis of what is sold under the name, and no evidence that it is stronger or safer than RAD-140. It is banned in sport and cannot legally be sold as a supplement in the US or UK.