MK 677 Side Effects & How To Avoid Them

In this article we’ll go over everything that you should know about MK 677 side effects.

We’ll go over the possible heart, liver, cancer and mental side effects as well as the long-term MK 677 side effects and how to avoid them.

MK 677 Side Effects

In order to fully understand the MK 677 side effects, we must first understand what this compound actually is, what it does and how it works.

Let’s jump right in.

MK 677, also known as Ibutamoren or Nutrobal, is a growth hormone secretagogue.

It’s frequently mistaken for a SARM but even though it’s often lumped into that category, it’s actually not a SARM at all.

It works by promoting the natural production of GH (Growth Hormone) and IGF-1 (Insulin-Like Growth Factor 1) in the body.

This has many benefits such as:

  • Increased muscle mass
  • Fat loss
  • Improved sleep
  • Improved hair and nails quality

Read more about MK 677 by reading our full Ibutamoren review.

MK 677 Side Effects

Let’s go over the possible MK 677 side effects one by one. We’ll split this section into 4 parts and go over these potential MK 677 side effects:

  • Side effects that affect the Liver
  • Cancer
  • Side effects that affect the heart
  • Mental side effects


MK 677 isn’t liver toxic in normal dosages. It doesn’t stay in the liver long enough to do any damage since it gets absorbed very quickly.

However, MK 677 can have some liver toxic properties when manufactured poorly. This is why it’s so important to you go with a high-quality, verified SARMs source.


MK 677 does not cause cancer. It can, however, speed it up.

Think of it like TRT (Testosterone Replacement Therapy), if you don’t have prostate cancer and you go on TRT, you won’t give yourself cancer. But if you already have it, Testosterone will likely make it progress faster than it would progress without Testosterone.


A lot of people believe that MK 677 can increase GH and IGF-1 to such supraphysiological levels that it can lead to heart growth. But what do the actual data and science say?

So far there are no studies supporting that MK 677 can cause heart growth.

MK 677 can’t take Growth Hormone or IGF-1 to such levels that it can directly cause heart growth. However, if you have incredibly high blood pressure, MK 677 could cause ventricular hypetrophy due to water retention. But if you have that high blood pressure you shouldn’t even think about compounds like MK 677 anyways.

Mental Side Effects

Some people report that they experience anxiety during their MK 677 cycle.

There’s 2 reasons why one would get anxiety when taking MK 677.

They are either very, very prone to anxiety to the point where almost any supplement they take causes anxiety for them. 

The second and most probable reason why one could get anxiety when taking ibutamoren is bunk MK 677. There is a lot of BS in the SARMs industry and a lot of people sell bunk products laced with other substances. 

It’s very possible that some of the people that report anxiety on their MK 677 cycle actually bought bunk products laced with substances that actually do cause anxiety.

Read more about this in our MK 677 anxiety article.

How To Avoid MK 677 Side Effects

There are 3 things that you should stick to in order to avoid side effects from MK 677.

Firstly, make sure that the MK 677 you buy is pure.

There are a lot of companies out there that sell bunk products in order to earn more money. Those products are often laced with prohormones or other substances which can cause a lot of side effects that real MK 677 wouldn’t cause.

Secondly, stick to low-medium dosages.

People who experience side effects from MK 677 or similar compounds usually also take very high dosages. Higher dosages have exponentially more side effects than lower dosages. Make sure to stick to low-medium dosages (up to 20mg per day).

Thirdly, don’t exceed 16 week long cycles.

MK 677 is a compound that should be cycled for maximum of 16 weeks at a time with at least a 10 week break between cycles. There have been some people that experienced nasty side effects and even long-term side effects from MK 677 because they have been on it for a year or even more!

Long-Term MK 677 Side Effects

We don’t have a lot of studies that are researching the long-term effects of MK 677. Because of this, we can’t know for sure if there are any long-term side effects from Ibutamoren usage.

The studies that we do have suggest that there aren’t any long-term side effects. However, there are only 2 studies that came to this conclusion. The first study was researching MK 677 usage over a period of two years. The second study did the same over a period of 18 months.

To summarize, we can’t be certain whether there are any long-term side effects or not when it comes to MK 677. The current evidence suggests that it’s safe but caution is warranted.


In conclusion, MK 677 has side effects that you need to keep in mind before starting to research with it on your own.

However, there are things that you can do in order to prevent experiencing side effects from MK 677.

Remember to stick to low dosages, short cycle length and to buy your compounds from a verified source.

If you have any questions, don’t hesitate to contact me and I’ll be glad to help.

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