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Andarine, commonly known as S4, is a popular Selective Androgen Receptor Modulator (SARM) in the fitness community due to its reported ability to help build lean muscle mass and reduce body fat.
However, before you get too excited, there are a few important things you should know about this substance.
In this article, we’ll cover everything you need to know about S4, provide an unbiased suggestion of trusted brands to source it from, and offer an honest review of its benefits, side effects, effectiveness, and safety. Let’s get started!
If you’re new to S4, it’s basically a type of substance categorised as a Selective Androgen Receptor Modulator, or SARM for short.
Understanding how it works is simpler than it seems: S4 selectively binds to androgen receptors in muscle and bone tissues, enhancing muscle growth and bone density while minimizing effects on other tissues.
Additionally, it aids in fat loss by promoting the oxidation of stored fat as energy.
This dual action makes it particularly appealing for body recomposition—where the goal is to build muscle while simultaneously losing fat.
The idea behind using SARMs like S4 is to mimic the effects of anabolic steroids while reducing the risks of its unwanted side effects, such as severe testosterone suppression.
When compared to other SARMs like LGD-4033 or RAD-140, S4 is often seen as a middle ground— it’s effective for cutting phases and body recomposition, but not as potent for sheer muscle mass gains as some of the stronger SARMs
Overall, S4 is a great choice for those looking to enhance their physique by building lean muscle and reducing fat without resorting to anabolic steroids. Its relatively mild side effect profile compared to other SARMs and steroids makes it a popular option among those new to SARMs!
Now that you’re more familiar with S4, the next important step is to choose a reputable brand for sourcing it.
While some businesses may promise quality, choosing well-established and positively recognized brands can offer greater assurance and safety when sourcing your substances.
With that in mind, we’ve carefully identified three of the most trustworthy brands offering Andarine S4 and provided a comparison based on their quantity/size, shipping, price, and overall ratings.
| Brand | Quantity | Shipping | Price | Rating |
|---|---|---|---|---|
|
60 capsules, 25mg/capsule |
|
$65.95 |
4.5/5 |
|
|
60 capsules, 12.5mg/capsule |
|
$45 |
4/5 |
|
|
27 tabs, 30mg/tab |
|
$59.48 |
4.3/5 |
To clarify why these ratings were given, here are the pros and cons for each brand:
Pros: Higher dosage per capsule, free shipping on orders over $100.
Con: Higher price per bottle compared to others.
Pros: Lowest price, relatively affordable shipping.
Con: Lower dosage per capsule compared to others.
While S4 is still classified as an investigational drug and its benefits are not fully confirmed, anecdotal evidence, preliminary research, and some clinical trials offer valuable insight into its effects.
Let’s take a closer look at these findings:
In a Reddit thread, a user shared his 6-week journey with S4 during a mini cut, highlighting both the benefits and the side effects commonly associated with it.
The user reported losing 8 pounds of fat while maintaining muscle mass, then by weeks 3-4, he noticed significant improvements in vascularity.
As for side effects, the infamous “yellow tint” began around week 2, along with mild light sensitivity and difficulty adjusting between light and dark environments.
But just as soon as S4 was discontinued, the vision disturbances disappeared within a day, and there were no signs of suppression, which indicates the substance’s mild impact on hormone levels.
Overall, S4 is considered less suppressive compared to other SARMs.
Preclinical research on S4 demonstrated its ability to restore levator ani muscle weight in castrated rats.
While the main focus of the study was to evaluate its potential for reducing prostate size—specifically as a treatment for conditions like benign prostatic hyperplasia (BPH)—S4 showed promise in its anabolic effects.
However, S4 was tested alongside S1, which proved more effective in reducing prostate and seminal vesicle weight. As a result, research on S4 was discontinued in favor of S1.
Though this may seem like a setback for medical applications, it’s positive news for recreational use, particularly in fitness, as it underscores S4’s milder anabolic and androgenic effects.
Despite being overshadowed by other SARMs like Ostarine, which had more successful trials, S4 remains a promising option for many users.
To get the best results from Andarine S4 while keeping side effects to a minimum, it’s essential to follow the recommended dosage guidelines.
Begin with a lower dose and adjust gradually based on your needs. Men typically take 25-50mg per day, while women should stick to 10-20mg daily.
Adjust your cycle length according to your experience and goals. Beginners can start with a 6-week cycle to monitor how their body responds, with an upper limit of 8 weeks.
Once you complete your S4 cycle, it’s a must to undergo post-cycle therapy (PCT) to help restore testosterone levels and address any suppression.
Although S4 is milder compared to other SARMs, taking these precautions ensures a safer experience.
Many SARMs users practice a technique called ‘stacking’ to enhance the benefits of their substances. However, it’s essential to understand that proper stacking requires careful attention, as improper use can pose risks.
To help you navigate this, below are two SARMs we recommend that you stack with S4 depending on your specific, desirable results.
The next section also includes guidelines on how to stack safely and effectively.
S4 and Cardarine complement each other well due to their distinct effects. S4 has notable anabolic properties, while Cardarine is known for boosting endurance. This combination can lead to increased muscle mass, reduced body fat, and overall improved performance at the gym.
Users report that Cardarine helps them power through their workouts more easily. They often notice a boost in energy and strength, allowing them to do more and feel less fatigued.
Given these benefits, combining S4 with Cardarine could be an excellent choice for those looking to enhance their endurance and physique by optimizing their workout sessions.
Stacking S4 with Ostarine is a common practice among SARMs users due to their synergistic effects on muscle development. Both substances enhance protein synthesis and muscle hypertrophy, working together to amplify results.
Ostarine, in particular, is known for its milder profile compared to other SARMs, making it a good choice for beginners. It also helps preserve muscle mass especially when on a caloric deficit, leading to a slimmer, leaner physique with noticeable gains.
If you’re new to SARMs and looking to improve your overall body composition, combining S4 with Ostarine might be your best option.
Before you start stacking SARMs, there are some important tips to keep in mind.
If it’s your first time combining specific SARMs, begin with the lowest recommended dose and adhere to the cycle duration suggested by your chosen brand.
This approach allows your body to gradually adjust to the substances and helps minimize potential side effects.
While some side effects may still occur, starting with a lower dose and following the recommended cycle can help keep them manageable and reduce the risk of severe issues.
Another important step is to undergo post-cycle therapy (PCT) after finishing your SARMs stack.
Even though SARMs are generally milder than steroids, they can still lead to side effects like testosterone suppression. To counteract this and minimize side effects, a PCT is essential.
Lastly, it’s crucial to remember that sticking to a training program and a specific diet is essential for achieving your desired results.
There’s no magic pill for getting your dream body—SARMs are simply tools to enhance the progress you make through your efforts!
Many SARMs are not suitable for women because of their potential severe effects on hormonal health. But what about S4? Can it be an exception, and is it considered a safer option?
The quick answer is yes.
S4 is generally considered a safer option for women when taken at appropriate doses, compared to many other SARMs.
Similar to Ostarine, S4 has a relatively mild impact on the body and is often used by women for its benefits in increasing muscle definition, improving strength, and aiding in fat loss.
Despite this, it’s important to be aware of the potential side effects of S4 so you can take extra precautions. Here are the key ones to watch for:
Note that these effects are usually temporary during the initial phase of taking S4.
However, if any of these symptoms persist or worsen, you should stop using the drug immediately and consult your healthcare professional.
In terms of dosage, females should take around 10-20mg only and also follow a 6-8 week cycle.
You might want to start with a lower dose and gradually increase it after a few days or a week, depending on how you feel.
As long as you stay within the recommended dosing range and allow your body to adjust to the drug gradually, you should be on the safe side.
Always remember that higher doses or longer cycles do not necessarily lead to more powerful or noticeable results.
In fact, they can be dangerous and should be avoided, especially if you’re a beginner.
To clarify why these ratings were given, here are the pros and cons for each brand:
This is the body transformation of a female user who incorporated Andarine S4 into her regimen.
Over an 8-week period, she committed to a well-structured S4 cycle which resulted in losing 15 pounds, significantly improving her overall body composition.
Her body fat percentage also decreased by 5% whilst approximately added 3 pounds of muscle mass.
Her cycle details are the following:
Post-Cycle Therapy (PCT): Not utilized in this cycle.
This next photo is of a male user who integrated Andarine (S4) and Cardarine into his regimen.
While the initial picture may appear slightly staged—showing him intentionally pushing out his belly—the results achieved from this stack are undeniably striking.
He lost 16 pounds, with his total body fat decreased by 8%, leading to a more defined physique.
The transformation highlights a well-developed six-pack, notably enhanced arms, shoulders, and traps, resulting in an overall impressive muscular appearance.
His cycle details are the following:
Post-Cycle Therapy (PCT): Not utilized in this cycle.
Frequently Asked Questions
Andarine (S4) is primarily used for cutting due to its ability to reduce body fat while preserving muscle mass. However, it can also support bulking by helping maintain muscle mass during a calorie surplus, though it is less commonly used for this purpose.
Andarine (S4) is banned by organizations like WADA because it is classified as a performance-enhancing drug, which can provide an unfair advantage in sports and pose health risks. Despite this, it continues to be used in recreational fitness for its benefits in muscle preservation and fat loss.
Negative side effects of S4 can include vision disturbances such as a yellow tint to vision and difficulty adjusting to low light, potential liver toxicity, and hormonal imbalances. Users might also experience headaches, nausea, and mood changes.
Yes, S4 can suppress testosterone levels. While it is generally less suppressive than anabolic steroids, it can still affect natural testosterone production, hence why PCT is needed.
Andarine S4 is highly regarded for its effectiveness in enhancing muscle growth while simultaneously reducing body fat, making it an excellent choice for body recomposition.
Its relatively mild side effect profile compared to other SARMs makes it especially suitable for those new to SARMs.
To ensure you are getting a high-quality product, choose a reputable brand like Paradigm Peptides, Swiss Chems, or PureRawz.
Don’t wait any longer—start your transformation journey today and take the first step toward achieving a leaner, stronger body!
DISCLAIMER: The information provided above is not intended to substitute professional medical advice, diagnosis, or treatment. Always seek your physician’s advice or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or read.We bear no responsibility or liability for your use of any compound.
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