S4 Dosage | The Best Andarine Cutting And Bulking Dosages

This is the ultimate S4 (Andarine) dosage guide.

We will go over:

  • The safest S4 dosage
  • The most optimal Andarine bulking dosage
  • S4 cutting dosage
  • Andarine dosage that was used in human trials

Almost every article on the internet talking about the best S4 dosage suggests a 50mg a day regimen for eight weeks.

There is a huge problem with that, as Andarine impairs vision at such a high dosage and nobody seems to care, despite numerous anecdotal reports claiming to have had negative experiences with the compound, examples being here and here.

I had a run-in with Andarine as well and driving while seeing yellow was definitely not a pleasant experience.

To avoid the yellow tint in vision, I propose one of two solutions: Either abandoning Andarine in favor of Ostarine or simply lowering the amount of Andarine consumed per day.

This article will entertain itself with the second idea.

Andarine or S4 is a SARM ranked as mild when measured up against all the other SARMs, and many people compare it to Ostarine in terms of benefits and potency.

It is not very suppressive, and people usually manage to recover post cycle without the need of PCT.

Human trials were never published; The one Phase I study on humans was abandoned when subjects who had taken Andarine began displaying disturbances in their vision.

The main benefits of Andarine are an increase in muscle mass, fat loss, the reduction of our prostate size and lastly, an increase in bone mineral density.

Learn all there is to know about this SARM in my Andarine review.

S4 Half-Life

The half-life of S4 has been determined to be just four hours. 

Although no papers or studies have ever been published specifically talking about the half-life of Andarine, other research on the subject cited four hours so we can trust the data on this one.

This means that Andarine has to be consumed multiple times a day in order to keep blood concentrations high. 

I think that four times a day is just the sweet spot, but you can already see how unconventional this SARM really is.

On the other hand, a similar SARM, Ostarine, only needs to be consumed once a day since it has a half-life of 24 hours.

S4 Bulking Dosage + Example Cycle

To be completely honest with you, people rarely bulk with Andarine since there are better options to choose from, but it can be done.

During a bulk with S4, you can expect to gain around 4-5 pounds of muscle mass and some fat loss should also be experienced.

Example of a bulking cycle:





20mgs a day


Remember to split the 20mg dosage in four equal parts. This means that you’re imbuing 5mgs of Andarine each time.

You don’t have to worry about Testosterone suppression at such a low dosage, you will do just fine.

S4 Cutting Dosage + Example Cycle

S4 really starts working wonders during a cut, it’s even better and a bit stronger than Ostarine at that task. 

It’s one of the reasons why I’m going through such great lengths to make Andarine presentable to the average user, instead of just dumping it in favor of Ostarine.

S4 preserves all of your muscle during a cut, it also helps build some lean muscle, and it aids in weight and fat loss.

Example of a cutting cycle:





20mgs a day


Once again, we’re opting for 20mgs a day split into four equal dosages. 

PCT is not going to be needed, as we’re taking measures to prevent the onset of Testosterone suppression in the first place.

Safest S4 Dosage

If it weren’t for the yellow tint in vision, one could technically consume up to 100mgs of Andarine per day without any further issues. 

However, this one side effect is quite serious and impairs the end user. Many bodybuilders live very active lives, and something messing with their vision is not really going to be welcomed.

With that being said, I think that the safest S4 dosage is 20mgs a day split into four equal dosages.

Such a regimen shouldn’t cause any issues with your vision, while still providing you with a noticeable boost in athletic performance.

Unfortunately, I can’t present any scientific evidence for my claims, but I think that my years of experience and self-experimentation speak loud enough.

What S4 Dosage Should I Take

In the end, it’s entirely up to you as to what and how much you will consume.

I can tell you one thing, at 50mgs of Andarine per day, you will not be able to drive a car reliably and that fact alone cripples you substantially.

While the aforementioned side effect goes away after you discontinue Andarine usage, you still have to live with the fact that for eight weeks, you’re basically a danger to yourself and others, at least on the road.

That’s why I wholeheartedly recommend taking it slow, consuming only 20mgs a day. 

Although highly unlikely, note that if you were to experience the yellow tint in vision even on 20mgs a day, immediately discontinue usage and switch to Ostarine.

If you’re a woman, 10mgs a day split into four equal dosages should be fine.

Be sure to have a dropper nearby in order to accurately measure the required dosage.


Consuming S4 is a bit like playing with fire. You won’t necessarily get burned, but you will feel the heat.

If you’re still hellbent on taking S4, please follow my recommended dosages and guidelines, in order to minimize the chances of side effects. 

50mgs of Andarine a day is most definitely going to impair your vision, so don’t even consider it.

All in all, I think that Ostarine is a far better choice since it has a longer half-life and it doesn’t screw with your vision.

more insights