NAD+, Glutathione & Sermorelin Cost: 2026 Price Guide

This article is sponsored by Yes Clinic.

Peptide therapy costs in 2026 depend mostly on where you buy. NAD+, glutathione, and sermorelin injections run roughly $100 to $500 a month. Through a telehealth clinic like Yes Clinic, NAD+ and glutathione run $159 for a month, and sermorelin runs $179, with a licensed clinician’s consultation included. In-person IV clinics usually charge more than that for a single session.

A few years ago, these three were niche. Now you see them at med spas, on podcasts, in your gym’s group chat and all over TikTok. Everyone seems to be “on peptides.” What rarely gets explained is what these compounds actually are, what a fair price looks like, and how to get them legitimately instead of from a random storefront.

That’s what this guide covers. We’ll go through each compound, real 2026 prices, the difference between telehealth, IV clinics and research-grade vials, and what you should check before you pay anyone.

Key takeaways

1. Only two of the three are peptides. Glutathione is a tripeptide and sermorelin is a 29-amino-acid peptide, but NAD+ is a coenzyme. It just gets sold alongside peptides. 🧬
2. Telehealth is the cheapest prescription route. Yes Clinic charges $159/month for NAD+ or glutathione and $179/month for sermorelin, with lower per-month rates on longer plans. 💵
3. IV clinics cost more per dose. A single NAD+ IV drip often costs $250 to $1,000+, and glutathione IVs typically run $150 to $300 per session. 💉
4. All three are compounded, not FDA-approved finished products. A prescription means a licensed U.S. pharmacy prepares it, with its name on your label. 🏥
5. Sermorelin is the only one of the three that was once an FDA-approved drug. It was sold as Geref until the manufacturer discontinued it in 2008 for commercial reasons, not safety ones. 📋

Why Peptides Are Suddenly Everywhere

The peptide boom has a few drivers. GLP-1 drugs like semaglutide made millions of people comfortable with at-home injections. Telehealth made prescriptions a 15-minute online form instead of a clinic visit. And the longevity crowd has turned “cellular energy” and “healthy aging” into mainstream goals.

The result is that compounds that used to live in anti-aging clinics are now sold direct to consumers. NAD+, glutathione and sermorelin are the three you’ll see most often, because they’re among the few that licensed U.S. compounding pharmacies can currently prepare with a prescription.

That legal status matters. Many of the peptides people discuss online, like BPC-157 or TB-500, have been in regulatory limbo. As of September 2026, an FDA advisory committee has voted in favor of adding several of them to the list of substances pharmacies can compound, but the FDA hasn’t made a final decision. NAD+, glutathione, and sermorelin don’t have that problem. That’s why every telehealth clinic seems to offer them.

What Are NAD+, Glutathione and Sermorelin?

Before we talk money, here’s what you’re actually paying for.

NAD+ (Nicotinamide Adenine Dinucleotide)

Is NAD a peptide? No. NAD+ is a coenzyme found in every cell in your body. It’s essential for turning food into cellular energy and for DNA repair enzymes like sirtuins and PARPs. It gets marketed with peptides because it’s sold through the same clinics, in the same injectable format.

The case for NAD+ comes from the fact that NAD+ levels decline with age, and that decline is linked to metabolic and age-related changes in animal studies. Human data is thinner. Most studies look at oral precursors like NR and NMN, and they show NAD+ levels go up but haven’t proven big functional benefits yet.

People use NAD+ injections for:

• Healthy aging and longevity protocols
• General wellness and recovery support

Glutathione

Is glutathione a peptide? Yes. Glutathione is a tripeptide made of three amino acids: glutamate, cysteine and glycine. Your liver makes it, and it’s often called the body’s “master antioxidant” because it neutralizes free radicals and helps with detoxification (Pizzorno, 2014).

Oral glutathione is partly broken down in the gut, which is one reason injections are popular. People use glutathione injections for:

• Antioxidant and liver support
• Recovery from oxidative stress, including heavy training

Sermorelin

Sermorelin is a synthetic version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). Instead of adding growth hormone to your body like HGH does, it signals your pituitary gland to release more of your own. That keeps your body’s natural feedback loops in place.

It’s also the only one of the three that was once an FDA-approved drug. It was sold as Geref and used to treat growth hormone deficiency, until the manufacturer discontinued it in 2008 for commercial reasons, not safety ones (FDA, Federal Register, 2013). Today it’s available as a compounded prescription.

People use sermorelin for:

• Sleep quality
• Body composition
• Recovery and general anti-aging goals

How Much Do NAD+, Glutathione and Sermorelin Cost in 2026?

Here’s the short version of peptide therapy costs for these three compounds. Prices depend far more on where you buy than on what you buy.

Market ranges based on published 2026 telehealth and clinic pricing. Yes Clinic prices as listed on yesclinic.com/peptides in September 2026.

NAD+ Injections Cost

At-home NAD+ injections through telehealth usually cost $105 to $350 a month. Watch for low introductory prices that jump after the first month, and for membership fees stacked on top of the medication.

At Yes Clinic, NAD+ is $159 for one month ($149 medication plus $10 shipping) and $419 for three months (about $140/month). The consultation is included, shipping is free on the longer plans, and there’s no membership fee.

For comparison, a single NAD+ IV drip at a clinic commonly costs $250 to $1,000 or more, depending on the dose. Some people run a loading phase of several drips, which can reach four figures in a week.

Glutathione Injection Cost

Glutathione is one of the cheapest injectables on the market. Telehealth programs that ship vials to your home run about $99 to $200 a month. IV sessions at wellness clinics typically cost $150 to $300 each, and “beauty drips” that add vitamin C or other extras often go higher.

Glutathione is $159 for one month, $419 for three months and $799 for six months. Months 4 to 6 ship after a month-3 check-in.

Sermorelin Cost

Sermorelin usually costs $150 to $250 a month through telehealth, and up to $500 a month at in-person anti-aging clinics that bundle in visits and labs. The medication itself is cheap to produce, so most of the price difference is the provider’s overhead.

At Yes Clinic, sermorelin is $179 for one month ($169 medication plus $10 shipping), $469 for three months (about $156/month) and $879 for six months (about $147/month). Months 4 to 6 ship after a month-3 check-in.

What If You Want All Three?

Plenty of people “stack” these compounds: sermorelin for sleep and body composition, NAD+ for energy, and glutathione for antioxidant support. Bought as separate one-month plans at Yes Clinic, all three come to about $500.

That’s real money, so it’s worth starting with the one that matches your main goal and adding others later if you actually notice a difference.

Where to Get NAD+, Glutathione and Sermorelin

You have three realistic options. Each one trades price, convenience and safety differently.

1. Telehealth Clinics (Best Balance of Price and Safety)

A telehealth clinic connects you with a licensed clinician online. If they approve treatment, a U.S. compounding pharmacy prepares your medication by name and ships it to your door. You get medical oversight and a licensed pharmacy, usually for less than an in-person clinic.

Yes Clinic is the telehealth option we point readers to for these three compounds. Here’s how the process works:

1. Pick your compound and plan length, and pay up front.
2. Fill out an online health intake.
3. A licensed clinician reviews it and decides if treatment is appropriate, and if testing is needed first.
4. If a clinician doesn’t prescribe, you aren’t charged for medication.
5. If you are, a licensed U.S. pharmacy compounds your medication and ships it in plain packaging, usually in a few business days.

What we like: clear pricing, no membership fees, and the consultation included. We covered the company in detail in our Yes Clinic review.

The limits: Yes Clinic only treats patients in the United States, availability varies by state, and its product pages don’t list the exact dose or vial count per plan. You’ll get those details from the clinician and the instructions that ship with your order.

Check out Yes Clinic’s peptide plans here.

2. IV and Med Spa Clinics

IV lounges and med spas are the most expensive route, but some people like the in-person experience and getting a large dose in one sitting. NAD+ IVs in particular can be uncomfortable when they’re pushed fast. Flushing, nausea and chest tightness are common reasons clinics slow the drip down, which is why sessions can take hours.

If you’re going the in-person route, ask where the clinic sources its NAD+ or glutathione, and whether a licensed provider is on site.

3. Research-Grade Vials

Some vendors sell lyophilized (freeze-dried) sermorelin and other compounds online at a fraction of clinic prices. These are not prescription products. There is no clinician, and no pharmacy standing behind what is in the vial. Quality depends entirely on the vendor’s own testing.

For NAD+ and glutathione, the price gap between that route and a prescription is small enough that the prescription route makes more sense for most people.

Side Effects and Safety

All three are generally well tolerated, but “well tolerated” isn’t the same as “risk-free.”

• NAD+: Flushing, nausea, cramping and fatigue, mostly when it goes in too fast. The FDA has received reports of severe chills, shaking, vomiting and fatigue after injectable NAD+ products.
• Glutathione: Injection-site irritation and, rarely, allergic reactions. Be skeptical of glutathione sold purely for skin lightening, especially from unlicensed sellers.
• Sermorelin: Injection-site redness, headache, flushing and occasional dizziness. It isn’t appropriate for people with active cancer, and anyone with endocrine conditions, or who is pregnant or breastfeeding, should talk it through with their clinician.

The other big safety point applies to all three. Compounded medications are not FDA-approved, and the FDA doesn’t review them for safety, effectiveness or quality before they’re sold. Licensed compounding pharmacies are still regulated under federal and state compounding laws, which is a very different standard from an anonymous online vendor.

How to Tell If a Provider Is Legit

Whichever route you pick, run through this checklist before you pay:

• A real clinician reviews your intake. If nobody asks about your health history, that’s a red flag.
• A licensed U.S. pharmacy, with its name on your label. It should not be “our lab” or an overseas supplier.
• Total pricing is clear. Check for membership fees, lab fees, and first-month discounts that disappear later.
• You aren’t charged for medication if a clinician doesn’t prescribe.
• Nobody promises results. Legit providers talk about what a compound is used for, not guaranteed fat loss or anti-aging miracles.

Conclusion

Peptides really are everywhere now, and NAD+, glutathione, and sermorelin are three you may run into the most. Only two of them are peptides, but all three are legal to get through a prescription, and prices have come down a lot as telehealth has taken over.

Telehealth beats IV clinics on price, and a prescription gives you a clinician and a licensed pharmacy. Expect to pay around $130 to $180 a month per compound through a clinic like Yes Clinic, and less on longer plans. Start with the compound that fits your main goal, give it a few months, and judge it by how you actually feel.

For more on the wider peptide world, browse our peptides hub.

DISCLAIMER: The information provided above is not intended to substitute professional medical advice, diagnosis, or treatment. Always seek your physician’s advice or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or read.We bear no responsibility or liability for your use of any compound.