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Peptide therapy cost in 2026 depends mostly on where you buy. NAD+, glutathione and sermorelin injections run roughly $100 to $500 a month. Through a telehealth clinic like YesClinic, NAD+ and glutathione run $159 for a month and sermorelin runs $179, with a licensed clinician’s consultation included. In-person IV clinics usually charge more than that for a single session.
A few years ago, these three were niche. Now you see them at med spas, on podcasts, in your gym’s group chat and all over TikTok. Everyone seems to be “on peptides.” What rarely gets explained is what these compounds actually are, what a fair price looks like, and how to get them legitimately instead of from a random storefront.
That’s what this guide covers. We’ll go through each compound, real 2026 prices, the difference between telehealth, IV clinics and research-grade vials, and what you should check before you pay anyone.
Key Takeaways💡
- Only two of the three are peptides. Glutathione is a tripeptide and sermorelin is a 29-amino-acid peptide, but NAD+ is a coenzyme. It just gets sold alongside peptides.
- Telehealth is the cheapest prescription route. YesClinic charges $159/month for NAD+ or glutathione and $179/month for sermorelin, dropping to about $133 and $147/month on 6-month plans.
- IV clinics cost more per dose. A single NAD+ IV drip often costs $250 to $1,000+, and glutathione IVs typically run $150 to $300 per session.
- All three are compounded, not FDA-approved finished products. A prescription through a licensed U.S. pharmacy gives you pharmacy-grade quality control that research vials don’t.
- Sermorelin has the strongest clinical track record of the three. It was an FDA-approved drug (Geref) until the manufacturer pulled it in 2008 for commercial reasons, not safety ones.
Why Peptides Are Suddenly Everywhere
The peptide boom has a few drivers. GLP-1 drugs like semaglutide made millions of people comfortable with at-home injections. Telehealth made prescriptions a 15-minute online form instead of a clinic visit. And the longevity crowd has turned “cellular energy” and “healthy aging” into mainstream goals.
The result is that compounds that used to live in anti-aging clinics are now sold direct to consumers. NAD+, glutathione and sermorelin are the three you’ll see most often, because they’re among the few that licensed U.S. compounding pharmacies can currently prepare with a prescription.
That legal status matters. Many of the peptides people talk about online, like BPC-157 or TB-500, have been in regulatory limbo. As of September 2026, an FDA advisory committee has voted in favor of adding several of them to the list of substances pharmacies can compound, but the FDA hasn’t made a final decision. NAD+, glutathione and sermorelin don’t have that problem. That’s why every telehealth clinic seems to offer them.
What Are NAD+, Glutathione and Sermorelin?
Before we talk money, here’s what you’re actually paying for.
NAD+ (Nicotinamide Adenine Dinucleotide)
Is NAD a peptide? No. NAD+ is a coenzyme found in every cell in your body. It’s essential for turning food into cellular energy and for DNA repair enzymes like sirtuins and PARPs. It gets marketed with peptides because it’s sold through the same clinics, in the same injectable format.
The case for NAD+ comes from the fact that NAD+ levels decline with age, and that decline is linked to metabolic and age-related changes in animal research. Human data is thinner. Most studies look at oral precursors like NR and NMN, and they show NAD+ levels go up but haven’t proven big functional benefits yet.
People use NAD+ injections for:
- Energy and mental clarity
- Healthy aging and longevity protocols
- Recovery from training and general fatigue
Glutathione
Is glutathione a peptide? Yes. Glutathione is a tripeptide made of three amino acids: glutamate, cysteine and glycine. Your liver makes it, and it’s often called the body’s “master antioxidant” because it neutralizes free radicals and helps with detoxification (Pizzorno, 2014).
Oral glutathione is partly broken down in the gut, which is one reason injections are popular. People use glutathione injections for:
- Antioxidant and liver support
- Recovery from oxidative stress, including heavy training
- Skin tone and brightness (the most hyped use, and the least supported by strong evidence)
Sermorelin
Sermorelin is a synthetic version of the first 29 amino acids of growth hormone-releasing hormone (GHRH). Instead of adding growth hormone to your body like HGH does, it signals your pituitary gland to release more of your own. That keeps your body’s natural feedback loops in place.
It’s also the only one of the three that was once an FDA-approved drug. It was sold as Geref and used to treat growth hormone deficiency, until the manufacturer discontinued it in 2008 for commercial reasons, not safety ones (Walker, 2006). Today it’s available as a compounded prescription.
People use sermorelin for:
- Deeper sleep, usually the first thing users notice
- Body composition, meaning less fat and more lean mass over months
- Recovery, skin quality and general anti-aging goals
We cover sermorelin in more depth, including research-grade sources, in our guide to buying sermorelin online.
How Much Do NAD+, Glutathione and Sermorelin Cost in 2026?
Here’s the short version of peptide therapy cost for these three compounds. Prices depend far more on where you buy than on what you buy.
Compound | Telehealth (monthly) | Yes Clinic (1 / 3 / 6 months) | In-person IV clinic |
NAD+ | $105 to $350 | $159 / $419 / $799 | $250 to $1,000+ per drip |
Glutathione | $99 to $200 | $159 / $419 / $799 | $150 to $300 per drip |
Sermorelin | $150 to $250 | $179 / $469 / $879 | $200 to $500/month at anti-aging clinics |
Market ranges based on published 2026 telehealth and clinic pricing. YesClinic prices as listed on yesclinic.com/peptides in September 2026.
NAD+ Injections Cost
At-home NAD+ injections through telehealth usually cost $105 to $350 a month. Watch for low introductory prices that jump after the first month, and for membership fees stacked on top of the medication.
At YesClinic, NAD+ is $159 for one month ($149 medication plus $10 shipping), $419 for three months (about $140/month) and $799 for six months (about $133/month). The consultation is included, shipping is free on the longer plans, and there’s no membership fee.
For comparison, a single NAD+ IV drip at a clinic commonly costs $250 to $1,000 or more, depending on the dose. Some people run a loading phase of several drips, which can reach four figures in a week.
Glutathione Injections Cost
Glutathione is one of the cheapest injectables on the market. Telehealth programs that ship vials to your home run about $99 to $200 a month. IV sessions at wellness clinics typically cost $150 to $300 each, and “beauty drips” that add vitamin C or other extras often go higher.
Yes Clinic prices glutathione the same as NAD+: $159 for one month, $419 for three months and $799 for six months.
Sermorelin Cost
Sermorelin usually costs $150 to $250 a month through telehealth, and up to $500 a month at in-person anti-aging clinics that bundle in visits and labs. The medication itself is cheap to produce, so most of the price difference is the provider’s overhead.
At YesClinic, sermorelin is $179 for one month ($169 medication plus $10 shipping), $469 for three months (about $156/month) and $879 for six months (about $147/month).
What If You Want All Three?
Plenty of people “stack” these compounds: sermorelin for sleep and body composition, NAD+ for energy, glutathione for antioxidant support. Bought as separate one-month plans at Yes Clinic, all three come to about $500. On six-month plans the total is $2,477, or roughly $413 a month.
That’s real money, so it’s worth starting with the one that matches your main goal and adding others later if you actually notice a difference.
Where to Get NAD+, Glutathione and Sermorelin
You have three realistic options. Each one trades price, convenience and safety differently.
1. Telehealth Clinics (Best Balance of Price and Safety)
A telehealth clinic connects you with a licensed clinician online. If they approve treatment, a U.S. compounding pharmacy prepares your medication by name and ships it to your door. You get pharmacy-grade quality control and medical oversight, usually for less than an in-person clinic.
YesClinic is the telehealth option we point readers to for these three compounds. Here’s how the process works:
- Pick your compound and plan length, and pay up front.
- Fill out an online health intake.
- A licensed clinician reviews it and decides if treatment is appropriate, and if testing is needed first.
- If you’re not approved, you get a full refund.
- If you are, a licensed U.S. pharmacy compounds your medication and ships it in plain packaging, usually within two to three business days.
What we like: clear pricing, no membership fees, the consultation included, and a refund if a clinician says no. We covered the company in detail in our YesClinic review.
The limits: YesClinic only treats patients in the United States, availability varies by state, and its product pages don’t list the exact dose or vial count per plan. You’ll get those details from the clinician and the instructions that ship with your order.
Check out YesClinic’s peptide plans here.
2. IV and Med Spa Clinics
IV lounges and med spas are the most expensive route, but some people like the in-person experience and getting a large dose in one sitting. NAD+ IVs in particular can be uncomfortable when they’re pushed fast. Flushing, nausea and chest tightness are common reasons clinics slow the drip down, which is why sessions can take hours.
If you’re going the in-person route, ask where the clinic sources its NAD+ or glutathione, and whether a licensed provider is on site.
3. Research-Grade Vials
Research peptide vendors sell lyophilized (freeze-dried) sermorelin and other peptides at a fraction of clinic prices. The catch is that these products are sold for research use only. There’s no prescription, no clinician, and no pharmacy standing behind what’s in the vial. Quality depends entirely on the vendor’s testing.
If you’re considering that route, read our research peptide buyer’s guide first. For NAD+ and glutathione, the price gap between research and prescription products is small enough that the prescription route makes more sense for most people.
Typical Dosing Protocols
Your clinician sets your dose. That said, it helps to know what common protocols look like so you can make sense of your prescription.
Sermorelin: Typically 200 to 300 mcg injected under the skin once a night before bed, to line up with the body’s natural overnight GH pulse. Many protocols run five nights on and two off, for at least three months. Sleep often improves in the first few weeks, while body composition changes take three to six months.
NAD+: At-home subcutaneous protocols commonly start around 50 mg and work up to 100 to 200 mg, two to three times a week. Starting low matters, because NAD+ causes flushing and discomfort when the dose climbs too fast.
Glutathione: Injectable protocols usually use 100 to 200 mg one to three times a week, either under the skin or into the muscle.
If you’re working out volumes from a vial, our peptide dosage calculator does the reconstitution math for you.
Side Effects
All three are generally well tolerated, but “well tolerated” isn’t the same as “risk-free.”
- NAD+: Flushing, nausea, cramping and fatigue, mostly when it goes in too fast. The FDA has received reports of severe chills, shaking, vomiting and fatigue after injectable NAD+ products.
- Glutathione: Injection-site irritation and, rarely, allergic reactions. Be skeptical of glutathione sold purely for skin lightening, especially from unlicensed sellers.
- Sermorelin: Injection-site redness, headache, flushing and occasional dizziness. It isn’t appropriate for people with active cancer, and anyone with endocrine conditions, or who is pregnant or breastfeeding, should talk it through with their clinician.
The other big safety point applies to all three. Compounded medications are not FDA-approved, and the FDA doesn’t review them for safety, effectiveness or quality before they’re sold. Licensed compounding pharmacies are still regulated under federal and state compounding laws, which is a very different standard from an anonymous online vendor.
How to Tell if a provider is legit
Whichever route you pick, run through this checklist before you pay:
- A real clinician reviews your intake. If nobody asks about your health history, that’s a red flag.
- A named, licensed U.S. pharmacy fills the prescription. Not “our lab” or an overseas supplier.
- Total pricing is clear. Check for membership fees, lab fees, and first-month discounts that disappear later.
- There’s a refund policy if you’re not approved.
- Nobody promises results. Legit providers talk about what a compound is used for, not guaranteed fat loss or anti-aging miracles.
Conclusion
Peptides really are everywhere now, and NAD+, glutathione and sermorelin are the three you’ll run into most. Only two of them are peptides, but all three are legal to get through a prescription, and prices have come down a lot as telehealth has taken over.
If you want the cheapest safe route, telehealth beats IV clinics on price, and a prescription beats research vials on quality control. Expect to pay around $130 to $180 a month per compound through a clinic like YesClinic, less on longer plans. Start with the compound that fits your main goal, give it a few months, and judge it by how you actually feel.
For more on the wider peptide world, browse our peptides hub.
FAQ's
Frequently Asked Questions
At-home NAD+ injections through telehealth usually cost $105 to $350 a month. Yes Clinic charges $159 for one month, $419 for three months and $799 for six months. A single NAD+ IV drip at a clinic typically costs $250 to $1,000 or more.
Sermorelin usually costs $150 to $250 a month through telehealth and up to $500 a month at in-person clinics. At Yes Clinic it costs $179 for one month, or about $147 a month on the six-month plan.
Not compared with most injectables. At-home glutathione typically costs $99 to $200 a month, while IV sessions usually run $150 to $300 each. Yes Clinic’s plans start at $159 for a month.
No. NAD+ is a coenzyme, not a peptide. It’s sold alongside peptides because the same clinics prescribe it in the same injectable format. Glutathione (a tripeptide) and sermorelin (a 29-amino-acid peptide) are true peptides.
For compounded injectables from a U.S. pharmacy, yes. A licensed clinician has to review your health history and approve treatment. Research-grade vials are sold without a prescription, but they’re labeled for research use only and don’t have pharmacy quality control.
Toggle CoThrough a licensed telehealth or in-person clinic that prescribes compounded sermorelin from a U.S. pharmacy. Yes Clinic offers sermorelin plans starting at $179 a month, with the consultation included.ntent
DISCLAIMER: The information provided above is not intended to substitute professional medical advice, diagnosis, or treatment. Always seek your physician’s advice or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or read.We bear no responsibility or liability for your use of any compound.
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