Cardarine, also known as GW 50156 is a compound that was developed to treat conditions like diabetes, heart disease. A lot of people talk about GW 50156 when they talk about SARMs (Selective Androgen Receptor Modulators). In reality, GW 50156 is not a SARM but it’s a PPARδ receptor agonist. In this article, we will go over everything about Cardarine. This is the best guide and review for this compound.
Let’s start off by explaining what Cardarine actually is.
What is Cardarine (GW 50156)
Cardarine is frequently in the conversation when we talk about SARMs (Selective Androgen Receptor Modulators) but it is actually a PPARδ receptor agonist (Peroxisome proliferator-activated receptor delta agonist) and not a SARM at all. It provides benefits like increased endurance, improved cardiovascular health and fat loss.
GW 50156 was designed in the 90s by Ligand Pharmaceuticals and GlaxoSmithKline to treat diseases like diabetes and cardiovascular diseases. It went through a lot of studies and trials but the compound was ultimately abandoned in 2007 when studies showed cancer development in rats. After that, a lot of people discussed this and even some studies were done that proved otherwise (we will talk more about that and if you should worry about this).
Even though Cardarine got abandoned because of safety concerns, athletes and other people started using it because of the amazing endurance benefits and fat loss it provides. Some people also use it to improve their cardiovascular health.
Shortly after people started using this compound, the WADA ( World Anti Doping Agency) added Cardarine and other PPARδ receptor agonists to the banned substances list.
How does Cardarine work
As we said, Cardarine is a PPARδ receptor agonist. This means that it binds to the PPARδ receptor to trigger some biological responses.
In muscles, Cardarine results in an increased oxidative capacity. This means more fat loss and bigger endurance.
The most important thing, however, is that GW 50156 replaces our energy source from glucose to fat. This has many benefits such as increased endurance, fat loss, increased cardiovascular health and more.
We will go over each benefit as well as the side effects and explain them in detail later in the article.
Is Cardarine Legal?
A lot of people think that Cardarine is illegal because it is not approved for human consumption by the FDA ( Food and Drug Administration). In reality, GW 50156 is legal to purchase and use as a “Research chemical” anywhere in the world.
This basically means that it is legal but can’t be sold without the label “Research chemical” because the FDA didn’t approve Cardarine for human consumption (because of safety concerns). So if you buy GW 50156 over the internet you won’t have any problems at all.
So to clear everything up, Cardarine is legal to buy and use in every country in the world as of 2020.
Cardarine in sports
Cardarine is prohibited if you are a competing athlete so please don’t take this compound if you compete in sports. GW 50156 has been banned by almost all sports bodies including the Olympics because of the obvious unfair advantages it gives (amazing endurance). GW 50156 is a prohibited compound for professional athletes by the USADA (the United States Anti Doping Agency) as well as the WADA (World Anti Doping Agency).
If you want to read more about this subject, read our article where we answer the question; is Cardarine legal.
Cardarine (GW 50156) Benefits
GW 50156 has great benefits of fat loss, increased energy, an incredible increase in endurance, improved cardiovascular health and more. We will go over each of these benefits.
- increased endurance
- fat loss
- improved cardiovascular health
- improved kidney and liver health
Now let’s go over each one in more detail.
This is the main benefit for athletes using Cardarine. It is so good that most people increase their endurance by over 40-60% in 30 minutes after taking the first dosage.
The main reason for this effect is because Cardarine suppresses glucose metabolism which results in increased endurance. This means that the body will use fat as fuel and not glucose which will make us burn fat and have more endurance.
You can expect to see increased endurance 30 minutes after your first dosage. You will get even better endurance week after week if you will run and train hard. And the best thing about this is, you can keep most of the endurance you gained during your Cardarine cycle if you continue to train and run after the cycle is over.
Most people instantly see around a 50% endurance increase. This means that if you are able to run 2 miles, you will easily be able to run 3 miles after the first dosage. A lot of people even say that being on GW 50156 feels like you have three lungs because you can breathe so easily. Some people even speculate that Lance Armstrong was using Cardarine or Stenabolic (or maybe even both) to win Tour de France 7 times).
This is another great effect of Cardarine that is also the main reason that a lot of people are using it. If you want to lose fat, we feel that Stenabolic could also be a great option for you so make sure to check it out.
GW 50156 will help you burn fat because it promotes the metabolism of fat cells. Basically, it will make us burn fat and not glucose. This has been proven in studies as well as animal testings on rats. Most people who use it to burn fat are usually able to burn a substantial amount of fat over the cycle. It is not uncommon for people to drop 5-7% body fat over 8-weeks with the help of Cardarine.
Remember, when it comes to fat loss, your diet and training will make the biggest impact. You can take as much of Cardarine or Stenabolic as you want, if you have a bad diet, it won’t make much of a difference.
Improved cardiovascular health
This is actually one of the main reasons Cardarine was researched and developed. Studies and animal testings on rats showed that GW 50156 has a very positive effect on our cardiovascular system. It reduced the damage done to rats, improved their blood vessels and reduced inflammation.
Even low doses of Cardarine were shown to clear up blood vessels which lowers the risk of heart attack and other cardiovascular diseases.
I will most likely use small dosages of Cardarine when I get older (over 50 years old) because of this benefit. It will allow me to have a very healthy cardiovascular system.
Improved liver and kidney health
Not a lot of people know this, Cardarine has a very positive effect on our liver and kidneys. This is really amazing because most similar compounds are actually liver or kidney toxic.
For kidneys, Cardarine showed that it reduces inflammation and studies found out that it lowers the chances of developing kidney disease.
GW 50156 also reduced the inflammation in the liver. It also switches the energy source from glucose to fat which is shown to improve our insulin resistance and this is beneficial for our liver.
Cardarine (GW 50156) Side Effects
A compound, that has all the benefits that we just listed makes you think that it has a bunch of side effects. In reality, GW 50156 actually seems to have only one side effect. This is also the reason the compound was abandoned in 2007, a study found that it caused the development of cancerous tumors in mice. We will go over this study and explain why you don’t need to worry about this.
Yes, a study was done that showed rapid development of cancerous tumors in mice and because of this Cardarine got abandoned from future clinical trials.
What most people don’t know, however, is that the dosages the rats received during that study were 50x the recommended amount. Not only that, but the rats were also receiving the dosages daily for 2 years straight! This is a lot more than the recommended 8-weeks cycles.
So yes, in very long periods of time and on very high dosages, we could be at risk of Cancer. But let’s be honest, nobody will do something like that. 50x the recommended dosage of pain killers would kill you, so dosages like that aren’t exactly a reason to completely throw away such an awesome compound like GW 50156.
But another study later found out that even at high dosages for short-normal cycle lengths, Cardarine shows no signs of cancer acceleration or tumor development. In addition, a clinical study on humans (10mg a day for 12-weeks) showed no signs of cancer or tumor development.
This means that as long as you use it at recommended dosages and not for almost a year straight, you won’t need to worry about this “side effect”.
So ask yourself: Will I use Cardarine at 10x the recommended dosage for over a year straight? If you say no, you don’t have to worry because it will only have great benefits and no such side effects. This recent study even showed that GW 50156 prevents cancer growth at normal dosages for normal cycle length.
My Cardarine experience
I have taken multiple cycles of Cardarine of 15mg a day for 8-weeks. I really like this compound especially because it has literally no side effects if you take it this way, two studies confirmed that it won’t cause anything to do with cancer for periods and dosages like this.
The last time that I took it, I stacked it with a small dosage of 10mg a day of Ostarine. This let me to easily get rid of all my fat and keep all my muscle mass (even gain some). It easily leaned me out, I lost my fat and dropped to about 9% body fat from 15 or 16% body fat. Keep in mind, I was careful with my diet and training as well.
Overall, this is a great compound in my eyes. I absolutely love the endurance benefit, it makes cardio easy for me. Not to mention all of the healing properties of Cardarine for the liver, kidneys and heart. I would say it’s very similar to Stenabolic but I feel like it is more effective at fat loss and endurance gain.
|1-8||15mg a day||10mg a day|
If you want to read my in-depth review, read my article about GW 50156 results.
As we said, Cardarine isn’t a SARM. It is also non-hormonal and won’t cause us to have a suppressed natural production of Testosterone.
This means that we don’t need a PCT (Post Cycle Therapy) for Cardarine. PCT is actually a very serious thing and can have serious side effects. This is why we shouldn’t do a PCT if we don’t need to. You definitely need a PCT with steroids but with SARMs that’s not the case.
GW 50156 results – Before and after
Now that we’ve covered my experience with this compound, let’s go over some real Cardarine reviews and results from other people.
We will go over the results from two people, if you want to read more reviews from other people, read our article about GW 50156 before and after. There we go over more before and after pics and their Cardarine cycles.
Cardarine results #1
|1-8||20mg a day|
This is a good example of what you can expect to see from your Cardarine cycle. He (the person in the photo) lost about 5% body fat and managed to keep most of his muscle mass.
Train at least 3-4 times a day as well as have a moderately clean diet and you will easily be able to achieve results like this using the same cycle as he did.
Cardarine results #2
|1-8||15mg a day||10mg a day|
As we can see, this is an example of a Cardarine – Ostarine cycle. He achieved decent results, nothing spectacular though. You should easily be able to achieve and surpass results like this with a decent diet and hard training. The person in the photo lost a few % of body fat and probably gained about two lbs of muscle mass.
You should be able to achieve results like this even without the help of Ostarine
Stacking Cardarine with SARMs
Cardarine is non-hormonal, it won’t cause any suppressed production of natural Testosterone. This means that we can easily stack it with any SARM without problems or complications.
We actually recommend that you stack it with SARMs like Ostarine or LGD-4033, depending on what you are trying to achieve. If you want to put on lean muscle mass and no fat, we recommend LGD-4033 and if you want to cut and keep all your muscle mass you should stack it with Ostarine.
Cardarine cycle examples
We will go over two Cardarine cycles. Cutting cycle and bulking cycle. Both of these examples are using SARMs with GW 50156. Keep in mind that if you want, you can cycle only GW 50156 as well.
This is a great cutting cycle, it will let you keep all your muscle and put on some as well. You will easily lose your fat and be full of energy. Don’t forget that diet and training will be very important, we can’t avoid that. We won’t need a PCT for this cycle. Ostarine is really mildly suppressive, our body will easily recover naturally in a few weeks after the cycle.
|1-8||15mg a day||10-15mg a day||/|
Lean bulk cycle:
This example is a great lean bulking cycle. We will gain only lean muscle and lose some fat at the same time as well. Keep in mind, training and diet will be very important, we won’t be able to avoid that. We also won’t need a PCT for this cycle. The LGD-4033 dosage isn’t high enough to cause problems and our bodies will easily be able to recover naturally after the cycle.
|1-8||15mg a day||2.5-10mg a day||/|
We recommend that you run a dosage of 10-25mg of Cardarine a day to see the best results. Beginners should obviously start at 10mg and work their way up. Dosages like were also shown to have no signs of risk of cancer so this is why we recommend that you stay in this range.
You should cycle Cardarine for 8-weeks. Some people do 12-weeks without problems but we still recommend 8 because a study that we mentioned earlier showed that this cycle length is safe and has no side effects.
GW 50156 has a half-life of 24 hours. This means that in order to keep the optimal levels of Cardarine in our body (to get the best possible results), we should take a dosage once every 24 hours. If you forget a dosage, don’t worry, just take the normal dosage (not a double) the next day and continue your cycle normally.
You can even take it a step further by splitting your dosage into two parts. Studies have shown that this is actually superior to taking one dosage a day. Although the difference is not that big, it’s still worth trying.
Take the first part in the morning and the second part in the evening. So for example, if you are taking 20mg of GW 50156 a day, take the first 10mg in the morning and the second 10mg in the evening.
You can read more about this in our article about Cardarine half-life where we answer the questions like; the best time to take GW 50156, etc.
When does Cardarine kick in
A lot of people aren’t sure how fast Cardarine actually kicks in. It’s important that we know this so that we can easily tell if our Cardarine is bunk or not.
When it comes to the increased endurance, Cardarine starts working in about 20 minutes after the first dosage and lasts throughout the whole cycle. Usually, the endurance starts gradually going down after the cycle, but if you do a lot of cardio even after the cycle, you can manage to keep most of the endurance.
Increased endurance is also a very easy way to tell if your GW 50156 is real. If you don’t get an increased endurance after the first dosage, try increasing your dosage. But if you still don’t get an increase in endurance even when you try 25mg a day, for example, you almost certainly have a bunk product.
The increased cardiovascular health also comes in very fast, in the first two weeks. Obviously, we can’t see this without doing a blood test, but it’s still good to know that our cardiovascular health will improve fast.
Some people who are using compounds that give our cardiovascular system a hard time (trenbolone, for example), love to use Cardarine because it makes it safe. They say that according to their blood tests, GW 50156 makes a huge positive difference in blood pressure, cholesterol levels, etc. in only a week.
Most people, however, are interested in the fat loss benefit. That takes a little bit longer to kick in compared to the endurance or the increased cardiovascular health. In my personal experience, you can expect to see the first signs of fat loss in the first two to three weeks of the cycle. Obviously, if you train hard and keep an eye on your diet, you will notice it faster.
On average, though, if you eat at calorie maintenance and train decently often, you will see fat loss progress by the end of the second or third week.
Tip: Take frequent photos of yourself, this way you will have an easy time tracking your progress.
If you prefer to get information about GW 50156 in video format, check out this YouTube video.
It’s a good video to get some information about Cardarine, but it’s less in-depth than this article.
Cardarine for sale
Obviously, if you want good results and no side effects from a compound like Cardarine, you have to make sure that you have high-quality, pure compounds. Some companies sell products like SARMs and GW 50156 but actually put very little of the actual compound into their products and put something else in there instead, like prohormones. This can obviously have serious side effects and won’t bring you the results you want.
This is why it’s so crucial that you buy your GW 50156 and other compounds from trusted companies that don’t sell bunk products.
We recommend that you buy your Cardarine from our recommended company. We tested their Cardarine and we can guarantee that it is pure and high-quality. You will experience incredible benefits from their compounds and won’t experience any side effects.
Plus, they have a 90-day money-back guarantee if you aren’t satisfied with the products, so you have nothing to lose.
In conclusion, Cardarine is a great product that has incredible benefits like:
- fat loss
- improved cardiovascular health
- improved kidney and liver health
A lot of people are scared off because people talk about cancer when they talk about GW 50156. In reality, this compound won’t cause cancer at normal dosages at all. In studies, rats got cancer because they received 50x the recommended dosage for almost two years straight.
Also, Cardarine is amazing when we stack it with compounds like Ostarine or LGD-4033. We can cut and keep all our muscles or bulk without putting on any fat. But don’t forget, these compounds aren’t magical pills that will let us do whatever, training and diet will still be very important and the most important factor for our results.
Don’t forget that you should always buy your compounds from trusted sellers like our recommended company, this way you can be sure of what you are getting.
Let’s go over some FAQ (Frequently Asked Questions) about Cardarine ( GW 50156) and answer them.
What Is Cardarine (GW 50156)?
Cardarine is a PPARδ receptor agonist that has benefits like improved endurance, cardiovascular health, fat loss as well as improved kidney and liver health.
How does Cardarine (GW 50156) work?
Cardarine will switch our energy source from glucose to fat. This means that we will burn off more fat and we will have more endurance.
What is the proper Cardarine dosage?
The proper Cardarine dosage is between 10-25mg a day. Beginners should start at 10mg a day.
What is Cardarine half-life?
The half-life of Cardarine is 24 hours. This means that we should take one dosage every 24 hours for the best results.
What side effects does Cardarine have?
A study found that Cardarine can cause the development of cancer. Keep in mind, the study used 50x the recommended dosage for 2 years straight.