Short answer: injectable SARMs are research-chemical products, usually oils or solutions sold under brand names such as “Ostalone” (ostarine) or “Ragebolone” (RAD-140), meant for intramuscular injection. No injectable SARM has ever been tested in a study: every human SARM trial used oral capsules or tablets. Claims that injecting avoids liver or cholesterol side effects are not established, and injecting an unregulated product adds infection risk on top of the drug’s own risks.
This guide covers what these products are, what is and isn’t known about injecting versus swallowing SARMs, safety, and quality.
Types of injectable SARMs
Injectable products are sold under brand-style names. Sellers describe them as follows; we have not verified what they contain, and “modified” versions of these compounds have not been described in any study we found:
- Ostalone
This is a modified version of Ostarine, also known as MK – 2866.
- Follitonic
This is a modified version of YK – 11.
- Cardiolone
This is a modified version of Stenabolic (SR – 9009) and Cardarine (GW – 50156). It’s often present as a mix of the two.
- Magnalone
This is a modified version of Ligandrol or LGD – 4033.
- Enudrablast
This is a modified version of SR – 9009, also known as Stenabolic.
- Winnyvar
This is a modified version of S-4 or Andarine.
- Ragebolone
This is a modified version of RAD – 140.
- Sarmbolone
This is a modified version of S-23.
SR9009 and cardarine (GW501516) are not SARMs. Cardarine is a PPAR-delta agonist and SR9009 is a REV-ERB agonist; neither acts on the androgen receptor, and neither has been shown to build muscle in people. They are sold alongside SARMs.
How to use injectable SARMs
We don’t give injection instructions for unapproved products, but anyone considering it should know the main risks, which are separate from the drug itself:
- Infection. Research chemicals are not made to sterile injectable standards. An unsterile product can cause abscesses and other infections even with a clean technique.
- Equipment. Needles and syringes are single-use. Boiling or otherwise “sterilizing” used needles, as the old version of this page described, is not safe, and sharing equipment risks blood-borne infections.
- Wrong product, wrong dose. An injectable dose is absorbed fully, so a mislabeled product has a bigger effect than the same error in a capsule.
- Get help early for redness, heat, swelling or fever at an injection site.
Injectable SARMs vs Oral SARMs
The old version of this page said injecting SARMs gives higher bioavailability, needs a lower dose and reduces the HDL and liver side effects. None of that has been tested:
| Claim | What is known |
|---|---|
| Higher bioavailability | Not measured for any injectable SARM. Oral SARMs are already well absorbed: LGD-4033 levels rose in proportion to the dose and built up threefold over 21 days (Basaria 2013) |
| Less HDL suppression | Not established. HDL fell in oral trials (ostarine −17% to −27%, Dalton 2011); no injection study exists |
| Less liver strain | Not established. The first-pass idea is theory; no study compared routes. Liver injury from SARMs has been described as idiosyncratic (Ladna 2023), not simply a first-pass effect |
| Faster onset | Not measured; for long half-life SARMs, steady levels build over days either way |
Oral use is the only route with human data. For taking liquids by mouth, see how to take liquid SARMs.
Are Injectable SARMs safe
No SARM is approved, and the FDA says products sold as SARMs are unapproved drugs that have been linked to serious risks including liver injury, heart attack and stroke (FDA). Injectable versions add the infection risks above and have no human data at all.
Product quality is the other problem. In a test of 44 products sold online as SARMs (Van Wagoner 2017):
- Only 23 (52%) contained one or more SARMs.
- 17 (39%) contained another unapproved drug instead or as well, including ibutamoren, GW501516 and SR9009.
- 4 (9%) contained no active compound; 11 (25%) contained substances not on the label.
- Only 18 (41%) contained the amount on the label; 26 (59%) differed substantially.
Side effects seen in oral SARM trials include lower testosterone, lower HDL cholesterol and raised liver enzymes; a systematic review of SARMs in healthy adults found raised ALT in about 7% of trial participants and 15 case reports of drug-induced liver injury (Vignali 2023). There is no reason to assume injecting avoids them.
Injectable SARMs for sale
Injectable SARMs are sold online as research chemicals. If you are in a country where buying them is allowed and still decide to, quality checks matter even more than for capsules:
- A third-party lab report (COA) for the exact batch, from a lab not owned by the seller, ideally including sterility and contamination testing, not only identity and purity.
- Avoid marketplaces such as Alibaba, eBay or Amazon listings for these products.
- Look for independent reviews, not just the seller’s own testimonials.
- Be wary of very low prices for injectables.
Our current partner pick for SARMs in general is SwissChems; what we checked and could not verify is in the SwissChems review. We have not verified injectable-specific quality such as sterility for any seller.
Conclusion
Injectable SARMs are marketed as cleaner and stronger than oral ones, but none has been studied: the benefits claimed for them (better absorption, less liver and cholesterol strain) are untested, while the extra risks of injecting an unregulated product are real. Every human SARM trial used oral dosing. If you are looking into SARMs, start with the evidence for each compound in the SARMs database.
Frequently asked questions
Are injectable SARMs better than oral?
Unknown; never testedEvidence: Limited
No injectable SARM has been tested in a study; every human SARM trial used oral dosing. Oral SARMs are already well absorbed.
Are injectable SARMs easier on the liver?
Not establishedEvidence: Limited
The first-pass idea is theory: no study has compared routes. SARM liver injury has been described as idiosyncratic, not simply a first-pass effect.
Do you inject SARMs?
Usually taken by mouthEvidence: Trial
Every human SARM trial gave them by mouth. Injectable products exist as research chemicals but are untested, and injecting them adds infection risk.
What is Ostalone?
A seller brand nameEvidence: Limited
A brand-style name sellers use for an injectable product described as modified ostarine. Its contents and effects have not been described in any published study.
Is it safe to inject SARMs?
No safety dataEvidence: Limited
There are no safety data for injected SARMs. On top of the oral side effects, unsterile research chemicals can cause abscesses and infections, and reused or shared needles are not safe.
Sources
- Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet
- The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men
- The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
- Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users
- Idiosyncratic drug-induced liver injury related to use of novel selective androgen receptor modulator RAD140 (Testalone): a case report
- FDA: Certain bodybuilding products put consumers at risk for heart attack, stroke, serious liver damage and more (content current as of 2 December 2025)